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  1. #1
    Atomic Punk
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    05.16.18 @ 11:48 AM
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    anti-malaria medication once routinely given to U.S. troops

    FDA warns about anti-malaria drug
    Mefloquine was once routinely given to U.S. troops, some of whom say it damaged them.

    Federal drug officials have issued a strong new warning about a controversial anti-malaria medication once routinely given to U.S. troops, some of whom say it damaged them permanently.

    The Food and Drug Administration ordered manufacturers of mefloquine hydrochloride to give the medicine a black box label, the agency's strongest warning, reserved for drugs with significant risks of serious side effects. The FDA said that some neurological and psychiatric side effects can last for months or years after a patient stops taking the drug.

    The medication was approved by the FDA in 1989 under the brand name Larium and quickly became a leading drug for preventing and treating malaria -- among travelers and the military.

    While other drugs must be taken daily, one tablet a week of mefloquine offers protection against the sometimes-deadly mosquito-borne parasite, including against strains that are resistant to other medications.

    But the drug has long carried warnings tying it to dizziness, seizures, insomnia, anxiety, depression and strange dreams. One clinical trial found that 29% of travelers who took mefloquine experienced at least one of those side effects. There is also evidence suggesting a link to violent behavior, including suicide.

    Amid growing concerns, the drug fell out of favor over the last decade. Roche, its original manufacturer, stopped selling Larium in the U.S. in 2008. The generic versions still on the market accounted for 226,000 of the 5.4 million U.S. prescriptions for anti-malaria drugs last year, according to IMS Health, which tracks drug trends.

    The Pentagon, which used the drug widely in Somalia and during the early years of the wars in Iraq and Afghanistan, offered little explanation when it began scaling back its reliance on mefloquine and eventually recommended that the drug be used only as a third choice.

    Military officials continued to dismiss the claims of veterans who insisted that the side effects could be long-lasting.

    The new FDA warning provided those veterans a sense of validation.

    "I almost fell out of my chair when [the news] was forwarded to me," said Greg Alderete, a retired Army lieutenant colonel who blames his chronic balance and memory problems on the drug, which he took while serving in Somalia in 1993.

    Alderete said that in 2008 he started to suspect mefloquine after connecting with other veterans of Somalia who were experiencing similar symptoms.

    He eventually helped launch a Facebook group, Veterans Against Larium, which now has more than 1,100 members. He said most served in Somalia, but the group has also attracted veterans from other wars.

    Alderete acknowledged that his depression, anger and anxiety could be the result of post-traumatic stress disorder, with which he was diagnosed.

    But his chronic dizziness and nausea and an inability to remember words are less easily explained.

    "There was a big gray zone," he said. "I'm not sure where mefloquine begins and PTSD ends."

    Doctors from the U.S. Department of Veterans Affairs have insisted that his problems are not related to the drug, he said.
    "Watch what people are cynical about, and one can often discover what they lack. -- Gen. George S. Patton

  2. #2
    Atomic Punk edwardv's Avatar
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    drop dead legs
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    05.20.18 @ 08:40 AM
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    All Lawyers line up here for lawsuits.
    EVH 1979: Well, actually it's not much of a vacation, because we run everything ourselves. We design our own album cover, we have to be in the office every day to sign checks - the whole corporation revolves around us. Nothing can be done without our approval. We even have photo approval.

  3. #3
    Summer Nights in Cabo SNIC's Avatar
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    03.28.18 @ 01:21 PM
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    Same stuff I took.

    Artists I Have Seen: 1D, 38 Special, Aerosmith, Alabama, Bad Company, Bad English, Billy Squire, Bob Seger, Bon Jovi, Boston, BTO, Cheap Trick, Chicago, Chickenfoot, Cinderella, Daughtry, Dave Matthews Band, Default, Def Leppard, Dio, Dokken, Drowning Pool, Eagles, Earth Wind & Fire, Eddie Money, Eric Clapton, Farenheit, Fleetwood Mac, Foreigner, Garth Brooks, George Strait, Glass Tiger, Heart, Huey Lewis and the News, Jackson Browne, Jimmy Buffett, Joan Jett and the Blackhearts, Joe Bonamassa, John Mellencamp, Journey, Keel, Kingdom Come, Kings X, KISS, Kool and the Gang, Krokus, Lionel Richie, Little River Band, Lou Gramm, Loverboy, Los Lonely Boys, Lynyrd Skynyrd, Metallica, Michael Bolton, Nickelback, Night Ranger, Paul Stanley, Peter Frampton, Pink Floyd, Poison, Red Rider, REO Speedwagon, Santana, Sammy Hagar, Shinedown, Steely Dan, Steve Miller Band, Styx, Ted Nugent, Tesla, The 1975, The Black Crowes, The Roots, The Wallflowers, U2, Van Halen, Whitesnake, Zac Brown Band, ZZ Top



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